Send Your Enquiry - Healingtouristry

Aplastic anemia is a condition which arises when the body stops producing enough new blood cells, or in other wordsit is a blood disorder in which the bone marrow (the soft tissue in the center of bones) doesn't make enough amount of blood cells.

Aplastic anemia develops when there is damage to bone marrow stem cells. When the cause remains unknown, it is known as idiopathic aplastic anemia.

Thus the causes of the disorder other than idiopathic fall into the "acquired" or "inherited" categories.

Acquired aplastic anemia (more common than the inherited form)

  • Exposure to toxins like benzene an ingredient in gasoline, pesticides and arsenichave been linked to aplastic anemia.
  • Radiation and chemotherapy treatments- when cancer-fighting therapies kill cancer cells, they can also damage healthy cells, including stem cells in bone marrow.
  • Infectious diseases- viral infections play animportant role in the development of aplastic anemia in some people. including hepatitis, HIV and Epstein-Barr virus (a type of herpes virus)
  • Auto immune disorder- lupus,rheumatoid arthritis, or other autoimmune disorders (those in which the immune system attacks healthy cells)
  • Pregnancy
  • Drugs-some antibiotics,immunosuppressants, and some NASIDs
  • Cancer which had spread in bone

Inherited aplastic anemia is rare and develops from genes that are passed down to next generation, includefanconi anemia, dyskeratosiscongenital, Diamond-Blackfan anemia, and Shwachman-Diamond syndrome

Clinical Sysmptoms And Signs

  • Nausea
  • Skin rashes
  • Anemia (low red blood cell count), neutropenia (low white blood cell count), or thrombocytopenia (low platelet count)
  • Fatigue
  • Shortness of breath and chest pain
  • Dizziness, especially after standing up from a sitting or lying position
  • Pale skin
  • Headaches
  • Weakness
  • Cold feeling in your hands and feet
  • Increased heart rate.

Thrombocytopenia may cause:

  • Bleeding that's difficult to stop
  • Easy bruising and bleeding
  • Tiny red dots on the skin
  • Nosebleeds, bleeding gums, bloody stool, or heavy menstrual bleeding.

Diagnosis

In aplastic anemia, the patient has pancytopenia (i.e., less blood count of all blood cells) - leukopenia and thrombocytopenia.

The diagnosis can only be confirmed on bone marrow examination. Before this procedure is undertaken, a patient will generally have had other blood tests to find diagnostic clues, including a complete blood count, renal function and electrolytes, liver enzymes, thyroid function tests, vitamin B12 and folic acid levels.

Treatment

Treatment is usually only necessary in severe cases of aplastic anemia that are causing life-threatening symptoms.

  • Blood Transfusion Platelet transfusions are the first course of treatment for any aplastic anemia patient who is severely deficient in platelet cells, thereby reducing the chance of fatal hemorrhage. Also, transfusions of red blood cells can help fighting the fatigue and shortness of breath. The procedure usually takes about one to two hours, depending on the blood component(s) you are receiving. Possible side effects include fever, allergic reaction or infection.
  • Bone Marrow Transplantation The patient's non-functioning bone marrow is destroyed with drugs and/or radiation and replaced with donor bone marrow from a compatible donor, usually a sibling or other family member. If successful, bone marrow transplant can cure aplastic anemia with few relapses. However, serious immune complications and infections may happen including sterility and temporary hair loss.
  • Medical Therapy Immunosuppressive drug therapy with anti-thymocyte globulin (ATG) and cyclosporine may be recommended for patients for whom bone marrow transplant is not an option. While drug therapy is not a cure for aplastic anemia, it may partially restore blood cell production. However, there may be 50% chance of relapse or developing other blood-forming malignancies or disorders. Side effects include fever, high blood pressure and kidney problems.
  • Supportive care Supportive care and long term follow-up are imperative in the management of aplastic anemia. A central venous catheter – a tube that carries medicines to a vein in the chest – may be helpful for aplastic anemia patients who require frequent transfusions or infused medications.Because fungal and bacterial infections are quite common in patients with severe aplastic anemia, patients may require antibiotics, antiviral or antifungal agents.

Get Expert Opinion and Free Personalized Quotation

border-head

Help us with your details

Send your Details
Get quotation within 12 Hours
Apply for Treatment
captcha

Hospitals

border-head

Indraprastha Apollo

Apollo Hospitals is widely recognized as the pioneer of private healthcare in India, and was the country`s first corporate hospital. The Apollo Hospitals Group,

More Detail

Fortis Hospital

Fortis Flt. Lt. RajanDhall Hospital, VasantKunj, New Delhi, is a 200 bed NABH certified multi-speciality tertiary care hospital. Spread over 1,50,000 sq. ft...

More Detail

Metro Hospital

With a vision to provide the utmost level of healthcare to the common man, at the most affordable cost,Dr. Purshotam Lal....

More Detail

BLK Hospital

Dr. B L Kapur, an eminent Obstetrician and Gynaecologist, set up a Charitable Hospital in 1930 at Lahore. In 1947, he moved to post-partition India...

More Detail

Action Cancer Hospital

Action Cancer Hospital, founded by Lala Mange Ram Aggarwal, is the first state-of-the-art cancer care hospital in the heart of West Delhi.

More Detail

Denvax Clinics

DENVAX is dendritic cell based cancer immunotherapy.

More Detail

Artemis Hospital

Sector 51, Gurgaon 122001 Haryana, India

More Detail

Fortis Escorts Heart Institute

Okhla Road, New Delhi - 110 025 (INDIA)

More Detail

Max Superspeciality Hospital Saket

Press Enclave Road, Mandir Marg, Saket, New Delhi 110017 India

More Detail

Columbia Asia

Block F, GolChakkar, Palam Vihar, Gurgaon, Haryana 122 017

More Detail

Fortis Memorial Research Institute, Gurgaon

Fortis Memorial Research Institute (FMRI), Gurgaon

More Detail

Medanata The Medicity

CH Baktawar Singh Road, Sector 38, Gurugram, Haryana 122001

More Detail

Paras Hospitals Gurgaon

C-1, SushantLok-1, Sector-43, Phase-I, Gurugram, Haryana 122002

More Detail

Dharamshila Narayana Superspeciality Hospital

Vasundhara Enclave, Near New Ashok Nagar Metro Station Delhi - 110096 (India)

More Detail

Narayana Multispeciality Hospital

Plot Number 3 & 4, Sadaramangala Industrial Area

More Detail

Fortis Malar Hospital

Fortis Malar Hospital 52, First Main Road, Gandhi Nagar, Adyar Adyar Chennai 600 020

More Detail

Manipal Hospitals

Manipal Hospitals, 98,Opposite, Leela Palace Road, Bengaluru, Karnataka 560017

More Detail

Apollo Hospital

No. 21, Greams Lane 320, Off. Greams Road, Chennai - 600006

More Detail

Gleaneagle Global Health city

439, Cheran Nagar, Perumbakkam, Chennai, Tamil Nadu 600100

More Detail

Seven Hills Hospital

Marol Maroshi Road, Shivaji Nagar JJC, Marol, Andheri East, Mumbai, Maharashtra 400059

More Detail

kokilaben dhirubhai ambani hospital

Rao Saheb, Achutrao Patwardhan Marg, Four Bunglows, Mudran Press Colony, Andheri West, Mumbai, Maharashtra 400053

More Detail

Wock Hardt Hospital

Wockhardt Towers BandraKurla Complex, Bandra (East) Mumbai 400051 Maharashtra, India

More Detail

Max Super Speciality Hospital Shalimar Bagh

C and D Block, Shalimar Place Site, Shalimar Bagh, New Delhi, Delhi 110088

More Detail

Doctors

border-head

Dr. Aloy J MukherjeeBariatric Surgery, General & Advanced Laparoscopic Surgery

Obesity. Hospital - Indraprastha Apollo, Sarita Vihar, Delhi

More Detail

Dr. Partha Prateem ChoudhuryInterventional Cardiology

Heart Care Institute. Hospital - Indraprastha Apollo, Sarita Vihar, Delhi

More Detail

Dr. Vinit SuriNeurology

Neurological Surgery. Hospital - Indraprastha Apollo, Sarita Vihar, Delhi

More Detail

Dr. Shuvendu Prosad RoyMBBS, MS-Orthopaedic Surgery

Orthopedics Surgery. Hospital - Fortis Hospital, Vasant Kunj, Delhi

More Detail

Dr. Gurinder BediMS, DNB, FRCS, FRCS-ortho

Orthopedics Surgery. Hospital - Fortis Hospital, Vasant Kunj, Delhi

More Detail

Dr. Jamal A. KhanMBBS MD

Cancer. Hospital - Denvax Clinics, Vasant Vihar, Delhi

More Detail

Dr. Hari GoyalDirector : Medical Oncology Unit II

Medical Oncology & Haematology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Monica BambrooHOD : Dermatology & Cosmetology

Dermatology & Cosmetology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Nidhi RawalPaediatric Cardiology

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Manjinder SandhuPaediatric Cardiology

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. SK RajanHead of Spine Surgery & Associate Director, Neurosurgery

Spine Decompression Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Anish GuptaHead & Neck Surgeon

ENT. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Anjana SatyajitDentistry

Dentures. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Arpit JainSenior Consultant

Internal Fixation of Fractures Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Ashu Kumar JainSr. Consultant

Anaesthesia & Pain Medicine. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Ashutosh ShuklaSr. Consultant

Internal Medicine. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. B.K. SinghSenior Surgeon

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Dheeraj KapoorSr. Consultant

Endocrinology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Hitesh GargConsultant Spine Surgeon, Artemis Health Institute, Gurgaon, Haryana

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. I P S OberoiOrthopaedics

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Ila GuptaReproductive Medicine

Obesity. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Kaushal MadanDigestive and Liver Diseases

Gastroenterology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Lakshmi Kant TripathiNephrology & Kidney Transplant

Nephrology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Paritosh S GuptaGeneral & MI Surgery

General & MI Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Rajesh K. VermaOrthopaedics

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Ramdip RayLiver Transplant & GI Surgery

Organ Transplant. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Aditya GuptaAdditional Director – Neurosurgery

Neurological Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Renu Raina SehgalSenior Consultant

Obesity. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Subodh Chandra PandeDirector - Radiation Oncology and Co-Director - Cyberknife Centre

Oncology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Akhil GovilCardio Thoracic and Vascular Surgery

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Himanshu GargHead

Respiratory Critical Care & Sleep medicine. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Geeta Baruah Nath Sr. Consultant

Obstetrics & Gynaecology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. S. V. KotwalMS General Surgery

Urology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Indu Bansal AgarwalSenior Consultant - Radiation Oncology

Radiation Oncology . Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Sameer KaushalSr. Consultant

Organ Transplant. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Nitin Goel GoelConsultant

Paediatric Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Sanjay SarupPaediatric Orthopaedics & Spine surgery

Pediatric Orthopedics & spine surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Shalabh AgrawalUrologist

Urology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Rajiv ChhabraSr. Consultant

Paediatric Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Sonu Balhara AhlawatSenior Consultant

Reproductive Medicine. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. T K ThusooSenior Surgeon

General & MI Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Shashidhar TBHead and Neck surgeon

ENT. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Vikram Barua KaushikAssociate Urologist

Urology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Sumit SinghDirector

. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Viresh MahajanDirector - Pediatric Cardiology

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Sumeet AgarwalHead

Rheumatology & Clinical Immunology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Noaline SinhaSr. Consultant

Nuclear Medicine. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Durgatosh PandeyDirector & Senior Consultant

Oncology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Biswajyoti HazarikaDirector- Surgical Oncology (Head & Neck)

Oncology. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Subhash Jangid Senior Consultant

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Veena Bhat Obstetrics & Gynaecology

Obesity. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Vipul Nanda Consultant - Cosmetic & Plastic Surgery

Plastic & Reconstructive Surgery. Hospital - Artemis Hospital, Gurugram Haryana

More Detail

Dr. Rohit MehtaHead of Department, Physiotherapy & Rehabilitation

Fractures. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Inder Mohan ChughAssociate Director & HOD - Interventional Pulmonology & Sleep Medicine

Bronchoscopy Procedure. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Manoj KhanalSenior Consultant Neurology

Back and Neck Pain. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Vineeta GoelAssociate Director, Radiation Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Mannu BhatiaConsultant - Orthopaedics & Joint Replacement

Orthopedics Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Naresh Kumar GoyalAssociate Director & HOD - Cardiology(Clinical & Research)

Cardiology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Naveen BhamriHead of Department & Associate Director Interventional Cardiology

Cardiology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Monisha GuptaConsultant - Gynae Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Vineet Govinda GuptaAssociate Consultant - Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Harsh WardhanSenior Consultant - Paediatric Surgery

Paediatric Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Yogesh ChhabraConsultant - Nephrology & Renal Transplantation

Kidney Transplant. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Raju EaswaranSenior Consultant - Orthopaedics & Sports Injury

Orthopedics Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Archit PanditConsultant - Surgical Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Rakesh K. DuaDirector & Head - Neurosurgery(Spine & Brain)

Neurological Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Nikhil AgnihotriSenior Consultant

Minimally Invasive Spine Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Anil Kumar VarshneyDirector & HOD - Urology

Urology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr.(Col.) Ranga Rao RangarajuDirector - Medical Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Rudra Prasad AcharyaMS(General surgery), Fellow(Surgical Oncology ft Colorectal Surgery), Sr. Consultant ft Head

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail

Dr. Gaurav DixitConsultant - Medical Oncology, Haematology and Bone Marrow Transplant

Bone Marrow. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

More Detail