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Diabetes Stem Cell Treatment

Diabetes is a ubiquitous life-long condition, which is now affecting younger generation as well. The number of children who are being diagnosed with type-1 diabetes is expanding. The prevalence of type-2 diabetes is higher in the adult population. The manifestations can be controlled; however, there is no fix. For some, diabetes implies daily insulin injections.

In the past few years, stem cell research has become a critical part of the scientific understanding of diabetes. Some promising results are out, which assert the use of stem cells in curing this condition.

What Causes Diabetes?

It is not possible to pinpoint the precise reason for diabetes More often than not, the body's own immune system erroneously pulverises the insulin-secreting (islet, or islets of Langerhans) cells in the pancreas. Other probable causes include:

  • If diabetes is running in the family, you are most likely to get it as well.
  • Lifestyle and environmental factors could be the cause of early occurrence of diabetes.

What are the Symptoms of Diabetes ?

The evident symptoms of diabetes are:

  • Increased thirst
  • Frequent urination
  • Loss of urinary control
  • Extreme hunger
  • Unintended weight loss
  • Fatigue and weakness
  • Blurred vision
  • Irritability and mood swings

How Does Stem Cell Treatment help in Curing Diabetes?

A standout amongst the most promising methodologies to cure diabetes is to transplant beta cells, which sense the fluctuation in glucose levels and produce insulin as per the patient's need.

  • Patients with type-1 diabetes would benefit because new beta cells would supplant the ones they'd lost to the ailment.
  • Patients with type- 2 diabetes could enhance their body's capacity to deliver insulin, bring down glucose levels and reduce the dependency on insulin injections.

How are the Stem Cells Administered?

  • Local Administration Through this mode, stem cells are explicitly implanted in the pancreas.
  • Intravenous Administration Stem cells are infused through the veins alongside the mannitol to enhance blood volume in the central nervous system. The intravenous method ensures that the injected cells reach the intended site.

Once implanted back in the body, these cells can be repopulated at the damaged parts of the pancreas through their substantial paracrine impacts, and proliferate into new beta cells. It is believed that vasculogenesis (differentiation of precursor cells) can help in generating new resistant cells.

What are the Long-term Goals of Stem Cell Treatment for Diabetes?

Stem cell treatment's popularity is increasing when it comes to finding a cure for Type-1 and Type-2 Diabetes.

The long-term goals of stem cell treatment for diabetes are to:

  • Increase life expectancy
  • Improve the stamina in everyday activities
  • Reduce the dependency on insulin injections
  • Prevent complications such as complete or partial blindness, heart disease, kidney failure and amputation of limbs.
  • Bring blood glucose levels under control with oral hypoglycemics.

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