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About The Treatment

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Myelodysplastic Syndrome (MDS) Treatment - Preleukemia

Myelodysplastic disorders (MDS, or myelodysplasia) are a group of diseases which affect, to a greater or lesser degree, the creation of healthy blood cells in the bone marrow. MDS happens because of a mutation (or change) in at least one of the genes that control platelet development. This results in the unusual growth of blood stem cells. A combination of radiation, chemotherapy and several similar methods are used to treat this syndrome.

What Causes Myelodysplastic Syndrome?

The causal factors for MDS are obscure to the medical fraternity. Some proof recommends that specific individuals are born with a tendency to get MDS. This propensity can be thought of as a switch that is activated by an external factor. In case the external factor can't be distinguished, the illness is alluded to as "primary MDS".

Radiation and chemotherapy for cancer are among the known triggers for the advancement of MDS. Patients who take chemotherapy medications or who get radiation treatment for possibly curable tumours, for example, breast or testicular cancer, Hodgkin's lymphoma and non-Hodgkin's lymphoma, are in danger of being diagnosed with MDS, which is usually followed by up to 10 years of treatment. MDS that happens after chemotherapy or radiation is classified "auxiliary or secondary MDS" and is typically connected to various chromosomal mutations in the bone marrow. This type of MDS often develops into acute myeloid leukaemia (AML).

What are the Signs You Should Look Out For?

People with MDS may experience the following symptoms or signs. The symptoms may or may not be visible in all people. These symptoms are common to most diseases, a proper diagnosis is advised.

  • Fatigue
  • Weakness
  • Fever
  • Bone pain
  • Shortness of breath
  • Frequent infections
  • Easy bruising or bleeding

How is MDS Diagnosed?

  • Complete Blood Count The complete blood count, or CBC, typically includes the following: White blood cell count (WBC or leukocyte count), WBC differential count, red blood cell count (RBC or erythrocyte count), haematocrit (Hct), haemoglobin (Hgb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), platelet count, and mean platelet volume (MPV).
  • Computed Tomography (CT) Scan A CT scan uses an x-ray machine to make a 3-dimensional photo of your body from inside. A PC at that point merges these pictures into a detailed picture that demonstrates any abnormalities or tumors. In some cases, the specialist will infuse a special dye (contrast medium) into a patient's vein to get more detailed pictures.
  • Conventional Cytogenetics This test takes a closer look at chromosomes (bits of DNA) under a magnifying instrument to discover any progressions. It's additionally called a karyotype. Since chromosomes can best be seen when the cell is separating, a sample of your blood or bone marrow must be developed in the laboratory. This diagnostic procedure is time-consuming.
  • Bone Marrow Biopsy The doctor will take red marrow sample from the back of your hip bone. This process is done under anaesthesia as it is slightly painful. The pathology lab that gets your marrow will verify whether your bone marrow is making healthy platelets. If not, the outcomes will demonstrate the cause, which might be an infection, bone marrow disease, or cancer.
  • Immunophenotyping Immunophenotyping is a test used to recognise cells based on the types of antigens display on the cell's surface, nucleus, or cytoplasm. This method distinguishes the genetic material of cells using antibodies that identify markers or antigens on the cells.

What Treatment Options are Available for MDS?

  • Chemotherapy Chemotherapy is the use of highly concentrated medications to obliterate cancer cells. It works by destroying the cells' ability to multiply.
  • Radiation Therapy Radiation treatment is the utilisation of high-energy x-rays or other particles to destroy cancerous cells. A radiation treatment calendar comprises a particular number of radiation therapies given over a set timeframe.
  • Bone Marrow Transplant A bone marrow transplant is a technique to supplant damaged, non-functional, or wasted bone marrow with new bone marrow from the donor. This minor medical procedure is performed under general anaesthesia. The bone marrow is removed from the back of both hip bones. The amount of marrow removed depends upon the need of the individual who needs it.
  • Blood and Platelets Transfusion You may have blood transfusions if your red platelets are low. What's more, if your platelets are low you will be given dribble of a clear liquid containing platelets.
  • Growth Factors Growth factors are drugs that urge your bone marrow to make more platelets. Erythropoietin is a growth factor that expands the number of red platelets. G-CSF yet another drug that increases the number of white platelets. The patient can take both of these medications as infusions through injections (subcutaneously).

Prognosis

Your specialist will meet you consistently to screen any difficulties you may experience. Further screenings may help forestall or mitigate any signs or manifestations. Screening, immunisations, and regular check-up will be used to monitor your recovery.

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Hospitals

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Indraprastha Apollo

Apollo Hospitals is widely recognized as the pioneer of private healthcare in India, and was the country`s first corporate hospital. The Apollo Hospitals Group,

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Fortis Hospital

Fortis Flt. Lt. RajanDhall Hospital, VasantKunj, New Delhi, is a 200 bed NABH certified multi-speciality tertiary care hospital. Spread over 1,50,000 sq. ft...

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Metro Hospital

With a vision to provide the utmost level of healthcare to the common man, at the most affordable cost,Dr. Purshotam Lal....

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BLK Hospital

Dr. B L Kapur, an eminent Obstetrician and Gynaecologist, set up a Charitable Hospital in 1930 at Lahore. In 1947, he moved to post-partition India...

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Action Cancer Hospital

Action Cancer Hospital, founded by Lala Mange Ram Aggarwal, is the first state-of-the-art cancer care hospital in the heart of West Delhi.

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Denvax Clinics

DENVAX is dendritic cell based cancer immunotherapy.

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Artemis Hospital

Sector 51, Gurgaon 122001 Haryana, India

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Fortis Escorts Heart Institute

Okhla Road, New Delhi - 110 025 (INDIA)

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Max Superspeciality Hospital Saket

Press Enclave Road, Mandir Marg, Saket, New Delhi 110017 India

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Columbia Asia

Block F, GolChakkar, Palam Vihar, Gurgaon, Haryana 122 017

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Fortis Memorial Research Institute, Gurgaon

Fortis Memorial Research Institute (FMRI), Gurgaon

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Medanata The Medicity

CH Baktawar Singh Road, Sector 38, Gurugram, Haryana 122001

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Paras Hospitals Gurgaon

C-1, SushantLok-1, Sector-43, Phase-I, Gurugram, Haryana 122002

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Dharamshila Narayana Superspeciality Hospital

Vasundhara Enclave, Near New Ashok Nagar Metro Station Delhi - 110096 (India)

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Narayana Multispeciality Hospital

Plot Number 3 & 4, Sadaramangala Industrial Area

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Fortis Malar Hospital

Fortis Malar Hospital 52, First Main Road, Gandhi Nagar, Adyar Adyar Chennai 600 020

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Manipal Hospitals

Manipal Hospitals, 98,Opposite, Leela Palace Road, Bengaluru, Karnataka 560017

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Apollo Hospital

No. 21, Greams Lane 320, Off. Greams Road, Chennai - 600006

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Gleaneagle Global Health city

439, Cheran Nagar, Perumbakkam, Chennai, Tamil Nadu 600100

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Seven Hills Hospital

Marol Maroshi Road, Shivaji Nagar JJC, Marol, Andheri East, Mumbai, Maharashtra 400059

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kokilaben dhirubhai ambani hospital

Rao Saheb, Achutrao Patwardhan Marg, Four Bunglows, Mudran Press Colony, Andheri West, Mumbai, Maharashtra 400053

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Wock Hardt Hospital

Wockhardt Towers BandraKurla Complex, Bandra (East) Mumbai 400051 Maharashtra, India

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Max Super Speciality Hospital Shalimar Bagh

C and D Block, Shalimar Place Site, Shalimar Bagh, New Delhi, Delhi 110088

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Doctors

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Dr. Aloy J MukherjeeBariatric Surgery, General & Advanced Laparoscopic Surgery

Obesity. Hospital - Indraprastha Apollo, Sarita Vihar, Delhi

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Dr. Partha Prateem ChoudhuryInterventional Cardiology

Heart Care Institute. Hospital - Indraprastha Apollo, Sarita Vihar, Delhi

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Dr. Vinit SuriNeurology

Neurological Surgery. Hospital - Indraprastha Apollo, Sarita Vihar, Delhi

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Dr. Shuvendu Prosad RoyMBBS, MS-Orthopaedic Surgery

Orthopedics Surgery. Hospital - Fortis Hospital, Vasant Kunj, Delhi

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Dr. Gurinder BediMS, DNB, FRCS, FRCS-ortho

Orthopedics Surgery. Hospital - Fortis Hospital, Vasant Kunj, Delhi

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Dr. Jamal A. KhanMBBS MD

Cancer. Hospital - Denvax Clinics, Vasant Vihar, Delhi

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Dr. Hari GoyalDirector : Medical Oncology Unit II

Medical Oncology & Haematology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Monica BambrooHOD : Dermatology & Cosmetology

Dermatology & Cosmetology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Nidhi RawalPaediatric Cardiology

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Manjinder SandhuPaediatric Cardiology

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. SK RajanHead of Spine Surgery & Associate Director, Neurosurgery

Spine Decompression Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Anish GuptaHead & Neck Surgeon

ENT. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Anjana SatyajitDentistry

Dentures. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Arpit JainSenior Consultant

Internal Fixation of Fractures Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Ashu Kumar JainSr. Consultant

Anaesthesia & Pain Medicine. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Ashutosh ShuklaSr. Consultant

Internal Medicine. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. B.K. SinghSenior Surgeon

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Dheeraj KapoorSr. Consultant

Endocrinology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Hitesh GargConsultant Spine Surgeon, Artemis Health Institute, Gurgaon, Haryana

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. I P S OberoiOrthopaedics

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Ila GuptaReproductive Medicine

Obesity. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Kaushal MadanDigestive and Liver Diseases

Gastroenterology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Lakshmi Kant TripathiNephrology & Kidney Transplant

Nephrology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Paritosh S GuptaGeneral & MI Surgery

General & MI Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Rajesh K. VermaOrthopaedics

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Ramdip RayLiver Transplant & GI Surgery

Organ Transplant. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Aditya GuptaAdditional Director – Neurosurgery

Neurological Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Renu Raina SehgalSenior Consultant

Obesity. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Subodh Chandra PandeDirector - Radiation Oncology and Co-Director - Cyberknife Centre

Oncology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Akhil GovilCardio Thoracic and Vascular Surgery

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Himanshu GargHead

Respiratory Critical Care & Sleep medicine. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Geeta Baruah Nath Sr. Consultant

Obstetrics & Gynaecology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. S. V. KotwalMS General Surgery

Urology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Indu Bansal AgarwalSenior Consultant - Radiation Oncology

Radiation Oncology . Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Sameer KaushalSr. Consultant

Organ Transplant. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Nitin Goel GoelConsultant

Paediatric Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Sanjay SarupPaediatric Orthopaedics & Spine surgery

Pediatric Orthopedics & spine surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Shalabh AgrawalUrologist

Urology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Rajiv ChhabraSr. Consultant

Paediatric Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Sonu Balhara AhlawatSenior Consultant

Reproductive Medicine. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. T K ThusooSenior Surgeon

General & MI Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Shashidhar TBHead and Neck surgeon

ENT. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Vikram Barua KaushikAssociate Urologist

Urology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Sumit SinghDirector

. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Viresh MahajanDirector - Pediatric Cardiology

Cardiology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Sumeet AgarwalHead

Rheumatology & Clinical Immunology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Noaline SinhaSr. Consultant

Nuclear Medicine. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Durgatosh PandeyDirector & Senior Consultant

Oncology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Biswajyoti HazarikaDirector- Surgical Oncology (Head & Neck)

Oncology. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Subhash Jangid Senior Consultant

Orthopedics Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Veena Bhat Obstetrics & Gynaecology

Obesity. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Vipul Nanda Consultant - Cosmetic & Plastic Surgery

Plastic & Reconstructive Surgery. Hospital - Artemis Hospital, Gurugram Haryana

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Dr. Rohit MehtaHead of Department, Physiotherapy & Rehabilitation

Fractures. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Inder Mohan ChughAssociate Director & HOD - Interventional Pulmonology & Sleep Medicine

Bronchoscopy Procedure. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Manoj KhanalSenior Consultant Neurology

Back and Neck Pain. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Vineeta GoelAssociate Director, Radiation Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Mannu BhatiaConsultant - Orthopaedics & Joint Replacement

Orthopedics Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Naresh Kumar GoyalAssociate Director & HOD - Cardiology(Clinical & Research)

Cardiology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Naveen BhamriHead of Department & Associate Director Interventional Cardiology

Cardiology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Monisha GuptaConsultant - Gynae Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Vineet Govinda GuptaAssociate Consultant - Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Harsh WardhanSenior Consultant - Paediatric Surgery

Paediatric Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Yogesh ChhabraConsultant - Nephrology & Renal Transplantation

Kidney Transplant. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Raju EaswaranSenior Consultant - Orthopaedics & Sports Injury

Orthopedics Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Archit PanditConsultant - Surgical Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Rakesh K. DuaDirector & Head - Neurosurgery(Spine & Brain)

Neurological Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Nikhil AgnihotriSenior Consultant

Minimally Invasive Spine Surgery. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Anil Kumar VarshneyDirector & HOD - Urology

Urology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr.(Col.) Ranga Rao RangarajuDirector - Medical Oncology

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Rudra Prasad AcharyaMS(General surgery), Fellow(Surgical Oncology ft Colorectal Surgery), Sr. Consultant ft Head

Oncology. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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Dr. Gaurav DixitConsultant - Medical Oncology, Haematology and Bone Marrow Transplant

Bone Marrow. Hospital - Max Super Speciality Hospital Shalimar Bagh, New Delhi

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